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Education|Local
UCLA team breaks chemistry rules to create new path for drug development
University of California, Los Angeles scientists have turned organic chemistry on its head by disproving a rule that’s been around for 100 years. Neil Garg and his team at UCLA showed that some supposedly impossible molecules can actually be made, publishing their work in science. Garg is the Kenneth N. Trueblood Distinguished Professor of Chemistry and Biochemistry at UCLA. Bredt’s rule, established in 1924, has long dictated that certain double bonds cannot exist at specific positions on organic molecules due to geometric constraints. This rule has limited chemists’ ability to design and synthesize certain compounds, particularly in drug discovery efforts.
November 13, 2024
